I-Beagnetic Beads isetyenziswa ikakhulu ekufundisisweni komzimba, i-molecular ixilongo, ukuhlanjululwa kwe-protein, ukuhlela kweseli, kunye nezinye iindawo
I-IglelodIagnosis: Ubusika be-i-Itonoruogractic yenziwa ngamasuntswana amalunga nezinto ezinamaqela asebenzayo. Iprotein ligands (i-antigens okanye ii-antibodies) zidityaniswe ngamaqela asebenzayo amaqela obuchwephesha, kwaye ke u-myossossay wenziwa usebenzisa i-protetic bead supers.
I-Molecular Discousis (i-Nuleic Acid): I-Nanoscale Beads enamaqela angaphandle anokwahlukaniswa kwaye aqiniseke ngentsimi yemagnethi, emva koko afumane i-template nycleid nucleid.
Ukucocwa kweprotheyini: Umnqamlezo onxulumene ne-agarose edityaniswe nge-prosein prothein a / g kumphezulu wobusika, iproteyini ebophayo yeProtina / iproteyini ekhethekileyo yokufumana ii-antibodies ezihlanjululwe.
Isifo sokuzithoba esinyaweni kunye ne-molecular
Enye yezicelo eziphambili ze-manynetic ubusika buxhomekeke kwisifo somzimba, apho besiyizixhobo ezingafanelekanga zokuhlolwa kwesifo ngokuchanekileyo. Uhlobo olukhethekileyo lwe-beads luvela kubuchule babo bokufumana kunye nokwahlula ii-antigens ezithile okanye ii-antibodies ezivela kwiisampulu zesigulana, ukwenza lula inkqubo yokuqonda. Ngokunxibelelanisa kakhulu iiproteni zeproteyini, ezinjengeebrigens okanye ii-antibodies, ukuya kumaqela asebenzayo amaBandla e-Magnetic, abaphandi banokwenza ucoceko ngokukuko nangokufanelekileyo.Ukuxilongwa kweMolekshini, enye indawo ebangela umdla, izibonelelo kakhulu ekusebenziseni ubuhlalu bamanzi. Ngobuchule bokuqonda isifo semolekyuli abafumana udumo kwiminyaka yakutshanje, ubuhlalu bamalungu bemagneri badlala indima ebalulekileyo ekukhetheni nasekukhokeleni i-acid ye-nucleic, njenge-DNA okanye i-DNA, kwiisampulu zebhayoloji. EZI ZIYABONAKALISA IZAKHONO ZOQOQOSHO, Ukuququzelela intsholongwane efanelekileyo kunye nokuhlanjululwa kweemolekyuli ekujoliswe kuzo. Le ndlela yokuhamba phambili incede izazinzulu ukuba zifezekise ulwazi oluchanekileyo noluthembekileyo, olukhokelela kwiziphumo ezingcono zesigulana.
Ukucocwa kweprotein kunye nokuhlela kweseli:
Ubudoda bemagneti bufuna ukuba busetyenziswe ngokubanzi kwiprotheyini yeProtein, inkqubo ebaluleke kakhulu kuPhuhliso lweziyobisi kunye ne-biochemistry yoPhando. Ngokudibanisa i-ligand ethile ukuya kwi-Beads, abaphandi banokukhetha ukubopha kwaye bakhuphe iiproteni zethagethi ngeendlela eziphantsi kunye nezivuno. Le ndlela yokucoca iyolisa kakhulu inkqubo yophando, ivumela izazinzulu ukuba zihlalutye neeproteni zokufunda ngendlela eneenkcukacha.Ukuhlelwa kweseli, kwicandelo elibalulekileyo lezicelo ezahlukeneyo zonyango nezixhobo zonyango, kusekwe elinye intsimi exhaswe kakhulu yi-manyticibys. Ezi zihlalo, zidityaniswe nee-biomarmars okanye ii-antibodies, ziququzelela ukuhlukaniswa kwezinto ezahlukeneyo zeseli. Ngokusebenzisa intsimi yemagneti, izazinzulu zinokuhlela ngokufanelekileyo kwaye zihlule iiseli ngokusekwe kwiimpawu zazo zomzimba nezisebenzayo. Ukukhululeka kunye nokuchaneka kolu buchule kuye komeleze iinzame zophando kwiinkqubo zeselfowuni ezintsonkothileyo, ezinjengenkqubela-phambili yomhlaza kunye nempendulo yomzimba.
IXESHA LOKUQALA: Jun-25-2023